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SUMMARY:Defense\, counter defense and counter counter defense in host path
 ogen interactions of plants - Professor Sir David Baulcombe\, Dept of Plan
 t Sciences\, University of Cambridge
DTSTART:20130116T123000Z
DTEND:20130116T133000Z
UID:TALK41788@talks.cam.ac.uk
CONTACT:Sue Griffin
DESCRIPTION:RNA silencing involving small interfering (si)RNA was revealed
   in plants from the finding that transgenes in plants were often unexpect
 edly silent. In some of the most counter-intuitive examples the silent tra
 nsgenes had a phenotype. They conferred resistance to viruses provided tha
 t there was sequence similarity of the virus and the transgene. \n\nThis o
 bservation then led to the discovery that RNA silencing is part of a natur
 al defense system in which viral RNA suppresses its own accumulation throu
 gh a negative feedback loop involving siRNA. Viruses produce protein suppr
 essors of RNA silencing as part of a counter defense system. \n\nIn my tal
 k I shall illustrate how the counter defense system is itself countered in
  the arms race between the host plant and its pathogens through the action
  of microRNAs.\n
LOCATION:Lecture Theatre\, Department of Pathology\, Tennis Court Road
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