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SUMMARY:Nature v. nurture:  dissecting the tumour ecosystem - Prof Gillian
  Murphy\, Department of Oncology
DTSTART:20130222T180000Z
DTEND:20130222T191500Z
UID:TALK42665@talks.cam.ac.uk
CONTACT:David de Sancho
DESCRIPTION:We have made tremendous progress toward understanding the gene
 tics of tumours in the past four decades\, but it is only recently that th
 e importance of the microenvironment\, has been appreciated. Communication
  between the cancer cells and the surrounding ‘stromal’ cells is vital
  for tumour progression. Enzymes that can cut the proteins of the tumour m
 atrix and of interactive signal pathways are key to processes such as grow
 th and metastasis. Evaluating the specific roles of individual proteinase 
 enzymes\, including their potential as therapeutic targets\, has been a su
 rprising challenge and has helped dissect the complex ecology of tumours.
LOCATION:Old Combination Room (OCR)\, Wolfson College
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