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SUMMARY:Oncogenes and Tumour Metabolism - Dr Mariia Yuneva\, National Inst
 itute for Medical Research (NIMR)
DTSTART:20130426T140000Z
DTEND:20130426T150000Z
UID:TALK43554@talks.cam.ac.uk
CONTACT:Dr Ireena Dutta
DESCRIPTION:Glucose and glutamine are two major nutrients that provide cel
 ls with ATP and intermediates for various biosynthetic processes. Glucose 
 and glutamine metabolism can interact in various metabolic pathways requir
 ed for cell proliferation and survival. This interaction varies among prol
 iferation and differentiation states and can be affected by multiple facto
 rs\, including oncogenes. We are using mouse models of tissue-specific tum
 ourigenesis to evaluate the relationship between distinct tumour-initiatin
 g lesions and changes in main pathways of glucose and glutamine metabolism
  in vivo. This approach should help to design more effective therapeutic s
 trategies tailored to specific types of tumours. 
LOCATION:Sackler Lecture Theatre\, CIMR\,  Level 7
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