BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:The Role of Glucose and Lipid Metabolism in Growth and Survival of
  Cancer Cells - Dr Almut Schulze\, Gene Expression Analysis Laboratory\, C
 ancer Research UK London Research Institute 
DTSTART:20130510T140000Z
DTEND:20130510T150000Z
UID:TALK43555@talks.cam.ac.uk
CONTACT:Dr Ireena Dutta
DESCRIPTION:\nThe hallmarks of cancer include uncontrolled proliferation\,
  reduced cell death and the loss of tissue homeostasis. The loss of normal
  control of cell growth and proliferation is the consequence of aberrant r
 egulation of cellular signaling pathways through the activation of oncogen
 es or loss of tumor suppressor function. Alterations in metabolic activity
  have emerged as one of the features of cancer cells and many oncogenic si
 gnaling pathways directly regulate the activity of metabolic processes. We
  have investigated the involvement of metabolic processes in the prolifera
 tion and survival of cancer cells. These studies demonstrated that cancer 
 cells have to balance their bioenergetics requirements with anti-oxidants 
 synthesis\, pH regulation and the activation of stress response pathways. 
 Disruption of this balance leads to loss of viability and may offer therap
 eutic opportunities. \n\nThis work was funded by Cancer Research UK.\n
LOCATION:Sackler Lecture Theatre\, CIMR\,  Level 7
END:VEVENT
END:VCALENDAR