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SUMMARY:Engineered protein pores in nanotechnology and single-enzyme studi
 es - Giovanni Maglia\,  Department of Chemistry\, University of Leuven\, B
 elgium
DTSTART:20130531T130000Z
DTEND:20130531T140000Z
UID:TALK45163@talks.cam.ac.uk
CONTACT:Shery Huang
DESCRIPTION:One goal of nanotechnology is the manufacture of tiny machines
  from simple parts\; another is the observation of single-molecule. Protei
 ns and DNA are ideal building blocks in nanotechnology because they can be
  precisely and reproducibly fabricated with atomic precision in large quan
 tity. Artificial devices made of natural components have the crucial advan
 tage over their synthetic equivalents of being able to interface with biol
 ogical systems.  Towards this end\, we built a nanopore:DNA systems that i
 s capable of controlling the transport of nucleic acids across biological 
 membranes. We also redesigned nanopore:protein systems that can recognize 
 specific protein substrates and allow the observation of folding\, activit
 y and dynamics of single-enzymes. 
LOCATION:Small Lecture Theatre\, Cavendish Laboratory
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