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SUMMARY:Statistics of DNA capture by a solid-state nanopore - Speaker to b
 e confirmed
DTSTART:20130809T130000Z
DTEND:20130809T140000Z
UID:TALK46660@talks.cam.ac.uk
CONTACT:Dr. Ulrich Keyser
DESCRIPTION:A solid-state nanopore can electrophoretically capture a DNA m
 olecule and pull it through in a folded configuration. The resulting ionic
  current signal indicates where along its length the DNA was captured. A s
 tatistical study using an 8-nm-wide nanopore reveals a strong bias favorin
 g the capture of molecules near their ends. A theoretical model shows that
  bias to be a consequence of configurational entropy rather than a search 
 by the polymer for an energetically favorable configuration. We also quant
 ified the fluctuations and length dependence of the speed of simultaneousl
 y translocating polymer segments from our study of folded DNA configuratio
 ns. 
LOCATION:Physics of Medicine Seminar Room\, PoM Building\, Cavendish Labor
 atory\, Department of Physics
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