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SUMMARY:Cutting as Untying (Topo2: Resolving the Gordian Knot of the Cell 
 since 3.8 billion B.C.) - Melissa Antoniou-Kourounioti\, Department of Gen
 etics\, University of Cambridge
DTSTART:20131114T131000Z
DTEND:20131114T140000Z
UID:TALK46959@talks.cam.ac.uk
CONTACT:Aleksandr Sahakyan
DESCRIPTION:Topoisomerases are a highly conserved family of enzymes found 
 in Archaea\, mammals and everything in between.  They are the enzymes resp
 onsible for relieving super- and under-coiled DNA and are thus a necessary
  component of every self-contained organism with nucleic acids.\n\nOur wor
 k focuses on how human topoisomerase (topo) 2α is regulated in the cell. 
  Particularly\, we are studying how SUMO modifications affect topo 2α act
 ivity and localisation through the cell cycle.
LOCATION:1 Newnham Terrace\, Darwin College
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