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SUMMARY:How can mice using iPads help cure Alzheimer's disease? - Professo
 r Tim Bussey (Department of Experimental Psychology\, University of Cambri
 dge)
DTSTART:20131104T190000Z
DTEND:20131104T203000Z
UID:TALK47071@talks.cam.ac.uk
CONTACT:Ivan Lam
DESCRIPTION:_This talk is free for members of BioSoc or £2 for non-member
 s. You can also sign up for life membership (£15) or annual membership (
 £10) at this talk._\n\nStrategies for cognitive translation from animals 
 to humans: The touchscreen testing platform for mice and rats.\n\nThe use 
 of animal models is an indispensable tool for the study of normal cognitio
 n\, and for understanding and discovering treatments for disorders of lear
 ning\, memory\, and other aspects of cognition\, such as those observed in
  Alzheimer’s disease. A major goal in the use of the animal models of co
 gnition is translation\, the ability successfully to transfer our behaviou
 ral results in animals to clinical studies in humans (and\, indeed\, back 
 again). To achieve this aim\, cognitive tests in animals should be as simi
 lar as possible to those used in humans. However\, many of the currently m
 ost widely used animal behavioural tests are in fact very dissimilar to th
 ose used with human subjects\, and criticism has been levied at animal res
 earch for using methodology that does not translate. In my talk I will dis
 cuss this problem\, and introduce the touchscreen approach to assessing co
 gnition in animal models\, in which mice and rats interact with an iPad-li
 ke touchscreen. This method provides the ability to test rodents on tasks 
 in many cases identical\, in all important respects\, to those we and othe
 rs have used in humans. By taking such an approach we have a better chance
  than ever of achieving successful translation from mouse and rat to human
  in the study of normal cognition\, and in discovering treatments for diso
 rders of cognition such as Alzheimer's disease.
LOCATION:Wolfson Lecture Theatre\, Department of Chemistry
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