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SUMMARY:Near-Field Electrospinning of Biomimetic Niche - Dr Yan Yan Shery 
 Huang\, CUED
DTSTART:20131101T140000Z
DTEND:20131101T150000Z
UID:TALK47875@talks.cam.ac.uk
CONTACT:Ms Helen Gardner
DESCRIPTION:Natural extracellular matrix (ECM) consists of well-defined ar
 chitecture and spatial patterns formed by fibril features ranging from nan
 ometre to micrometre scale. Constructing biointerfaces which recapitulate 
 the essential topological cues of an ECM can help elucidate the key mechan
 otransduction pathways. It can also reveal the role of micro-environments 
 in controlling primary cell processes\, including differentiation\, migrat
 ion and proliferation. The proposed work focuses on developing topological
 ly defined biomaterial constructs for controlled mechano-biology research.
  I will show you our recent development in this area\, which involves a bi
 o-mechanically regulated cancer migration assay\, as well as guided assemb
 ly of vascular network. It is envisaged that NFES may provide a facile and
  versatile bio-fabrication platform\, offering the possibility to personal
 ised therapeutic implants for tissue regeneration and drug screening.
LOCATION:Oatley Seminar Room\, Department of Engineering
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