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SUMMARY:X-ray phase contrast imaging - detecting the undetectable - Sandro
  Olivo\, Dept of Medical Phys &amp\; Bioengineering\, University College L
 ondon
DTSTART:20131108T140000Z
DTEND:20131108T150000Z
UID:TALK47962@talks.cam.ac.uk
CONTACT:Dr Eileen Nugent
DESCRIPTION:X-ray Phase Contrast imaging (XPCi) generates image contrast f
 rom interference and refraction effects instead of x-ray attenuation\, whi
 ch leads to enhanced visibility of all details and to the detection of fea
 tures classically considered "x-ray invisible". \n\nXPCi thus has great po
 tential in a wide range of applications\, from the earlier diagnosis of le
 sions in medical imaging to the detection of faint blemishes in non-destru
 ctive testing.\n\nHowever\, XPCi seemed to require a high level of (at lea
 st spatial) coherence\, which restricted its use to synchrotron facilities
 . Microfocal sources can be used but\, due to low emitted flux\, result in
  exposure times too long (hours) for most practical applications. Other at
 tempts were based on aperturing/collimating the focal spot of a convention
 al source to create sufficient spatial coherence\, again limiting the sour
 ce output and resulting in excessive exposure times and/or delivered dose.
 \n\nAfter briefly reviewing previous implementations\, I will present a me
 thod\, based on appropriately designed x-ray masks\, which works with unap
 ertured and uncollimated conventional x-ray sources\, at acceptable exposu
 re times and delivered doses. I will describe how the method works\, expla
 in how quantitative features can be extracted from the images\, and provid
 e examples of application in various fields.\n\nFinally\, I will show how 
 this same method\, if implemented with coherent sources\, leads to phase s
 ensitivities much higher than in other approaches\, and briefly mention th
 e new areas of research that this can enable. \n
LOCATION:Small Lecture Theatre\, Cavendish Laboratory
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