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SUMMARY:Intrabodies for Huntington's and Parkinson's disease therapeutics 
 - Anne Messer\, Ph.D.  Professor of Biomedical Sciences\, University at Al
 bany  Senior Scientist\, Neural Stem Cell Institute  Albany/ Rensselaer\, 
 NY\, USA
DTSTART:20131113T140000Z
DTEND:20131113T150000Z
UID:TALK48741@talks.cam.ac.uk
CONTACT:35426
DESCRIPTION:Accumulation of misfolded proteins characterizes several impor
 tant neurodegenerative diseases\, including Huntington’s and Parkinson
 ’s. The specificity and engineering potential of antibody fragments offe
 rs multifunctional approaches to modify the toxic effects of such proteins
 . By targeting the proteins intracellularly\, intervention can occur at th
 e earliest stage in a pathogenic cascade. Huntington’s offers particular
 ly robust models and the can serve as a paradigm for related disorders.
LOCATION:University of Cambridge  Department of Chemistry Pfizer Lecture T
 heatre
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