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SUMMARY:Physico-chemical properties of colloids\, their interaction with c
 ells\, and some applications - Prof Wolfgang Parak\, Biophotonics Group\, 
 University of Marburg\, Marburg Germany
DTSTART:20140117T140000Z
DTEND:20140117T150000Z
UID:TALK50193@talks.cam.ac.uk
CONTACT:Dr Eileen Nugent
DESCRIPTION:Modern synthesis methods allow for obtaining colloidal nano- a
 nd microparticles with highly defined properties. With these particles det
 ailed studies about their interaction with the environment are possible. T
 his will be described for the cases of adsorption of counter ions and prot
 eins [1\, 2] and impact on interaction with cells will be discussed [3\, 4
 ]. Some in vitro sensing and delivery applications will be highlighted [5\
 , 6].\n\n[1] 	P. Rivera Gil\, D. Jimenez de Aberasturi\, V. Wulf\, B. Pela
 z\, P. del Pino\, Y. Zhao\, J. de la Fuente\, I. Ruiz de Larramendi\, T. R
 ojo\, X.-J. Liang\, W. J. Parak\, "The Challenge To Relate the Physicochem
 ical Properties of Colloidal Nanoparticles to Their Cytotoxicity"\, Accoun
 t of Chemical Research 46\, 743–749 (2013).\n[2]	M. Mahmoudi\, A. M. Abd
 elmonem\, S. Behzadi\, J. H. Clement\, S. Dutz\, M. R. Ejtehadi\, R. Hartm
 ann\, K. Kantner\, U. Linne\, P. Maffre\, S. Metzler\, M. K. Moghadam\, C.
  Pfeiffer\, M. Rezaei\, P. Ruiz-Lozano\, V. Serpooshan\, M. A. Shokrgozar\
 , G. U. Nienhaus\, W. J. Parak\, "Temperature Effects at the Nano-Bio Inte
 rface"\, ACS Nano 7\, 6555–6562 (2013).\n[3] 	D. Hühn\, K. Kantner\, C.
  Geidel\, S. Brandholt\, I. De Cock\, S. J. Soenen\, P. Rivera Gil\, J. M.
  Montenegro Martos\, K. Braeckmans\, K. Müllen\, G. U. Nienhaus\, M. Klap
 per\, W. J. Parak\, "Polymer-coated nanoparticles interacting with protein
 s and cells: Focusing on the sign of the net charge"\, ACS Nano 7\, 3253
 –3263 (2013).\n[4]	M. Chanana\, P. Rivera Gil\, M. A. Correa-Duarte\, L.
  M. Liz-Marzán. W. J. Parak\, "Physicochemical Properties of Protein-Coat
 ed Gold Nanoparticles in Biological Fluids and Cells before and after Prot
 eolytic Digestion"\, Angewandte Chemie 52\, 4179–4183 (2013).\n[5]	L. L.
  del Mercato\, A. Z. Abbasi\, M. Ochs\, W. J. Parak\, "Multiplexed Sensing
  of Ions with Barcoded Polyelectrolyte Capsules"\, ACS Nano 5\, 9668–967
 4 (2011).\n[6]	M. Ochs\, S. Carregal-Romero\, J. Rejman\, K. Braeckmans\, 
 S. C. De Smedt\, W. J. Parak\, "Light-Addressable Capsules as Caged Compou
 nd Matrix for Controlled Triggering of Cytosolic Reactions"\, Angewandte C
 hemie 52\, 695-699 (2013).\n
LOCATION:Small Lecture Theatre\, Cavendish Laboratory
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