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SUMMARY:Growth and form of the gut - Dr Thierry Savin\, CUED
DTSTART:20140131T140000Z
DTEND:20140131T150000Z
UID:TALK50258@talks.cam.ac.uk
CONTACT:Ms Helen Gardner
DESCRIPTION:The pattern in which intestines are folded within the body cav
 ity is conserved between individuals and characteristic of species. This r
 eproducible form and structure is governed by simple mechanics related to 
 the way the body grows during embryogenesis. Throughout development the gu
 t tube\, anchored to a muscular sheet called the mesentery\, grows faster 
 than the body surrounding it\, forcing it to loop. We used developmental a
 nd biophysical experiments (mathematical theory and both computational and
  physical models) to determine what drives the characteristic looping\, fo
 cusing on the chick gut. We demonstrated that pattern in which the gut loo
 ps is determined solely by the tissue-scale elasticity\, geometry and rela
 tive rates of growth of the mesentery and gut. This model accounts for var
 iation in gut patterns\, during development and in a range of species incl
 uding quail\, finch and mouse.
LOCATION:Oatley Seminar Room\, Department of Engineering
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