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SUMMARY:Cell death and autophagy in response to inhibition of glycolysis -
  Dr Cristina Muñoz Pinedo\, IDIBELL\, Barcelona\, Spain
DTSTART:20140304T120000Z
DTEND:20140304T130000Z
UID:TALK50290@talks.cam.ac.uk
CONTACT:Dr Ireena Dutta
DESCRIPTION:Tumor cells are highly glycolytic and depend on glucose for su
 rvival. Our laboratory is trying to understand how cells die when they lac
 k glucose or when they are treated with 2-deoxyglucose\, a non-metabolizab
 le glucose analog. I will give an overview of work in our lab regarding th
 e differences in cell death mechanisms induced by these treatments. I will
  also discuss the role of autophagy as a protective mechanism against sele
 ctive nutrient deprivation or anti-metabolic treatments.
LOCATION:Sackler Lecture Theatre (Level 7)\, Cambridge Institute for Medic
 al Research
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