BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:A dynamic view of fMRI connectivity: Frequency dependent cortical 
 hubs and network integration in the human brain. - Peter Fransson\, Karoli
 nska Institute\, Stockholm\, Sweden
DTSTART:20140527T100000Z
DTEND:20140527T110000Z
UID:TALK50456@talks.cam.ac.uk
CONTACT:Mikail Rubinov
DESCRIPTION:It is well known that the large-scale functional MRI connectom
 e of the human brain is composed of a manifold of so called resting-state 
 networks (RSNs). However\, the network dynamics\, such as integration and 
 segregation between and within RSNs are largely unknown. In this talk\, I 
 will describe some recent work done in our research group that addresses t
 his question. Using a novel frequency analysis method together with graph 
 theory we analyzed the frequency dependency of low-frequency BOLD fMRI res
 ting-state signal (0.01–0.1 Hz) in a cohort of 80 subjects. Our results 
 show that the existence of functional hubs\, the central nodes of the netw
 orks\, fluctuates as a function of frequency and that the membership of hu
 bs to different RSNs shifts dynamically across frequency. Further\, we sho
 w that the global network efficiency and network integration is peaking at
  0.07 – 0.08 Hz. In my talk\, I will discuss the observed frequency depe
 ndence on the spatial configuration of hubs and its implications for our u
 nderstanding of the dynamics of large-scale network integration and  segre
 gation in the human brain.
LOCATION:MRC CBU lecture theatre\, 15 Chaucer Road
END:VEVENT
END:VCALENDAR