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SUMMARY:Preclinical and Clinical Animal Models in Translational Orthopaedi
 c Research - Matthew J. Allen\, Vet. M.B.\, Ph.D.Department of Veterinary 
 Clinical Sciences\, The Ohio State University\, Columbus\, OH 
DTSTART:20140226T161500Z
DTEND:20140226T171500Z
UID:TALK50486@talks.cam.ac.uk
CONTACT:Fiona Roby
DESCRIPTION:Preclinical and Clinical Animal Models in Translational Orthop
 aedic Research\nMatthew J. Allen\, Vet. M.B.\, Ph.D.\n\nDepartment of Vete
 rinary Clinical Sciences\, The Ohio State University\, Columbus\, OH \n\nT
 he use of animals in research remains controversial. While efforts should 
 always be made to replace animal use through the use of in-vitro alternati
 ves such as cell culture or computer simulation\, there remains a clear ne
 ed for in-vivo studies to better define disease mechanisms and evaluate ne
 w therapies. In this presentation\, I will review our experience with the 
 use of preclinical animal models in musculoskeletal research\, with a part
 icular emphasis on orthopedic oncology\, spine surgery and total joint rep
 lacement. I will also discuss the tremendous opportunities that exist in u
 sing clinical cases seen in the veterinary hospital as a natural bridge be
 tween the research laboratory and eventual clinical deployment of new medi
 cal and surgical treatment options in both humans and animals. \n
LOCATION:Lecture Theatre 2\, Department of Veterinary Medicine
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