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SUMMARY:Minimal models of self-assembly and protein crystallization in viv
 o - Dr Jonathan Doye\, (Department of Chemistry)
DTSTART:20060623T091500Z
DTEND:20060623T100000Z
UID:TALK5089@talks.cam.ac.uk
CONTACT:Duncan Simpson
DESCRIPTION:In biology\, there are many remarkable examples of self-assemb
 ly\, such as virus capsids or complex multi-component assemblies\, such as
  the ribosome or flagellum motor. However\, I cannot hope to simulate the 
 assembly of such systems at an atomistic level. Instead\, I take a differe
 nt approach\, and explore minimal models that can reversibly assemble into
  a target structure. These models allow the thermodynamics and dynamics of
  the\nassembly process to be studied in detail. The hope is that some of t
 he principles learnt will also be of relevance to the biological cases. Fu
 rthermore\, the principles of how to design the interactions to achieve\ns
 elf-assembly should also be helpful to nanotechnologists.\n\nIf time allow
 s\, I will also provide some examples from a rather neglected area of biol
 ogical self-assembly\, namely the crystallization of proteins in the cell.
 \n\n
LOCATION:Emmanuel College Cambridge
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