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SUMMARY:Systems biology view of mutualistic interactions - Ulrich Johan Ku
 dahl
DTSTART:20140502T120000Z
DTEND:20140502T122500Z
UID:TALK51402@talks.cam.ac.uk
CONTACT:Megan Cooper
DESCRIPTION:\nApplication of microalgae for industrial purposes holds grea
 t potential and can aid in worldwide challenges such as food and energy sh
 ortage. The cost of added nutrients\, such as vitamins and the cost associ
 ated with contamination from other microorganisms are currently two factor
 s limiting the use of microalgae biotechnology. By co-culturing algae with
  appropriate bacteria\, that can supply key nutrients and limit the opport
 unities for foreign organisms\, it is possible to improve the efficiency o
 f microalgae production systems and expand the industrial opportunities. M
 y project will be based on the symbiosis model system of the bacterium Mes
 orhizobium loti and the microalga Lobomonas rostrata\, where vitamin B12 i
 s produced by the bacterium and supplied to the algae in return for a carb
 on source. I study their mutualistic interaction from a systems biology po
 int of view using techniques such genome scale metabolic reconstruction an
 d flux balance analysis to identify the metabolites and pathways involved 
 in the interaction. In the first year of my project I have developed a gen
 ome scale metabolic reconstruction of M. loti and applied it to study orga
 nic energy sources useable by the bacterium.
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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