BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Engineering tissue morphogenesis in vitro - Dr Alison P McGuigan\,
  University of Toronto Department of Chemical Engineering and Applied Chem
 istry
DTSTART:20140328T140000Z
DTEND:20140328T150000Z
UID:TALK51696@talks.cam.ac.uk
CONTACT:Ms Helen Gardner
DESCRIPTION: During tissue regeneration\, replacement cells are recruited 
 and re-organized into a specific arrangement. The functionality of the reg
 enerated tissue depends critically on correct incorporation and re-organiz
 ation of these replacement cells during the regenerative process. Historic
 ally the signals that guide cell re-organization\, or morphogenesis\, to p
 roduce tissue patterning have been studied extensively in developing embry
 os using various animal models. The complexity of embryo morphogenesis and
  the interplay between multiple signals at multiple length scales make thi
 s a particularly challenging process to dissect however\, and animal model
 s often do not easily allow combinations of different signals to be pertur
 bed systematically. In this talk I will present some of the in vitro model
 s we are developing to allow systematic analysis of the signals that direc
 t cell re-organization for carefully dissecting the regulatory systems tha
 t control tissue re-organization. These cell culture systems offer the pot
 ential for high-throughput screening to identify therapeutic strategies\, 
 such as drugs or biomaterials\, for modulating and controlling cell re-org
 anization and tissue morphogenesis.
LOCATION: Cambridge University Engineering Department\, LR5
END:VEVENT
END:VCALENDAR