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SUMMARY:Regulators of inflammatory responses - Dr. Thirumala-Devi Kannegan
 ti\,  St Jude Children's Research Hospital\, Memphis\, USA
DTSTART:20140618T151500Z
DTEND:20140618T161500Z
UID:TALK51937@talks.cam.ac.uk
CONTACT:Fiona Roby
DESCRIPTION:Inflammation plays vital roles in protective responses against
  pathogens and tissue repair\, however\, improper resolution of inflammato
 ry networks is centrally involved in the pathogenesis of many acute and ch
 ronic diseases. Extensive advances have been made in recent years to defin
 e the inflammatory processes that are required for pathogen clearance\, ho
 wever\, in comparison\, less is known about the regulation of inflammation
  in sterile settings. Over the past decade non-communicable chronic diseas
 es that are potentiated by sterile inflammation have replaced infectious d
 iseases as the major threat to global human health. Thus\, improved unders
 tanding of the sterile inflammatory process has emerged as one of the most
  important areas of biomedical investigation during our time. Our studies 
 describe the cellular events and molecular signalling pathways regulated b
 y NLRs and IL-1 that govern sterile inflammation in autoinflammatory disea
 se.
LOCATION:Lecture Theatre 2\, Department of Veterinary Medicine
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