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SUMMARY:Cellular models for Tissue Engineering: potential and limitations 
 - Professor C. James Kirkpatrick\, Johannes Gutenberg University
DTSTART:20140516T130000Z
DTEND:20140516T140000Z
UID:TALK52264@talks.cam.ac.uk
CONTACT:Ms Helen Gardner
DESCRIPTION:For the author there are three major challenges in Tissue Engi
 neering (TE)\, namely to\ndevelop strategies which are translatable\, mate
 rials which are responsive and methods\nwhich are predictive. New strategi
 es in TE depend on a concerted interdisciplinary effort\nbetween the exact
  and engineering sciences on the one side and the life sciences\, includin
 g\nmedicine on the other. A further major task of the life sciences is to 
 understand the so-called\n„regenerative niche“\, which differs from ti
 ssue to tissue. Great progress made in stem cell\nbiology has opened up ne
 w vistas on the possibility to target a regenerative niche. However\,\nwe 
 still need to understand regeneration in hostile environments\, as are pre
 sent following\ntrauma and in cancer and multimorbidity. This will be disc
 ussed using examples from the\nauthor’s own research\, which involves co
 culture systems consisting of relevant human cells\nwith and without compl
 ex 3D biomaterial scaffolds. Lessons learned from so-called „cellular\nc
 rosstalk“ and the relevance of the latter for TE will be discussed.\n\nS
 upported by the EU Institute of Excellence\, EXPERTISSUES\, and research g
 rants from the German Research Foundation (DFG) and the BMBF/DAAD German-C
 hinese Cooperation in Regenerative Medicine.
LOCATION:Oatley Seminar Room\, Department of Engineering
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