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SUMMARY:Genome wide characterization of Foxa1/2 binding sites reveals mult
 iple mechanisms for regulating neuronal specification and differentiation 
 in midbrain dopamine cells.  - Dr Emmanouil Metzakopian\, Wellcome Trust S
 anger Institute
DTSTART:20140521T110000Z
DTEND:20140521T120000Z
UID:TALK52447@talks.cam.ac.uk
CONTACT:Shannon Tinley-Browne
DESCRIPTION: The transcription factors Foxa1 and Foxa2 promote the specifi
 cation of midbrain dopaminergic neurons. To better understand their functi
 ons\, we characterized the Foxa1/2 cis-regulatory network by chromatin imm
 unoprecipitation followed by high-throughput sequencing of dopamine neuron
 s using in vitro and in vivo mouse models. The results highlight important
  mechanisms critical to midbrain dopamine neuron development.
LOCATION:Brain Repair Centre\, Forvie Site\, Robinson Way
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