BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:'Scottish Collaboration On Translational Research into Renal Cell 
 Cancer (SCOTRRCC): a springboard for renal cancer biomarker development’
 .  - Mr Grant Stewart\, Clinical Senior Lecturer and Honorary Consultant i
 n Urological Surgery\, University of Edinburgh 
DTSTART:20140722T110000Z
DTEND:20140722T120000Z
UID:TALK52887@talks.cam.ac.uk
CONTACT:Mala Jayasundera
DESCRIPTION:Mr Grant D Stewart is the Senior Clinical Lecturer in Urologic
 al Surgery at the University of Edinburgh and Honorary Consultant Urologic
 al Surgeon at Western General Hospital\, NHS Lothian\, Edinburgh. \n\nGran
 t is a practicing urological surgeon with clinical expertise in kidney can
 cer surgery and leads the Edinburgh Urological Cancer Group\, undertaking 
 translational research into renal cell cancer (RCC). Grant directs the Sco
 ttish Collaboration On Translational Research into Renal Cell Cancer (SCOT
 RRCC) a Scotland-wide kidney cancer bio-repository with high quality clini
 cal data linkage. To date biosamples (fresh frozen\, FFPE\, blood\, urine)
  have been collected from 950 patients as part of SCOTRRCC\, leveraging tr
 anslational kidney cancer research across Scotland. \n\nOver a 5y post-doc
 toral career Grant has been awarded >£2.6 million research funding and to
  date published 73 peer reviewed publications (h-index=19). Mr Stewart is 
 a member of the National Cancer Research Institute Renal Cancer Clinical S
 tudies Group\, Chair of the Renal Cross Channel Group\, PI for several ren
 al cancer clinical trials\, supervises 5 PhD students and is Course Direct
 or for RCSEd/University of Edinburgh ChM in Urology. \n\nIn addition to SC
 OTRRCC\, Grant has been successfully coordinated a 387 patients prostate c
 ancer diagnostics trial\, resulting in a commercially available test in US
 A (ConfirmMDx).\n\nIn his seminar\, Grant will outline the reasons for fai
 lure to develop prognostic and predictive biomarkers in RCC and the unique
  challenges that translational research into RCC brings. The SCOTRRCC infr
 astructure and associated experimental approaches will be outlined which i
 ncorporate many ideal practices in RCC biomarker research using a systems 
 biology framework. Grant will illustrate the successful utilization of SCO
 TRRCC to develop the theme of intratumoural heterogeneity and the effect o
 f targeted drug therapy on this process. Finally\, putative predictive and
  prognostic biomarker signatures developed in the face of intratumoural he
 terogeneity will be outlined. \n
LOCATION:CRI Lecture Theatre\, Cambridge Research Institute
END:VEVENT
END:VCALENDAR