BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY: The first heart beat: initiation of cardiac contractile activity 
 - Dr. Shankar Srinivas - Department of Physiology\, Anatomy and Genetics -
  University of Oxford
DTSTART:20140605T150000Z
DTEND:20140605T160000Z
UID:TALK52921@talks.cam.ac.uk
CONTACT:Philipe Mendonca
DESCRIPTION:I will discuss recent unpublished work from my group looking a
 t the earliest contractile activity during mammalian embryogenesis. We fin
 d that the developing heart starts to beat already at the cardiac crescent
  stage\, considerably earlier than the linear heart tube stage as widely b
 elieved. We find foci of contractile activity on the right and left sides 
 of the cardiac crescent that beat at the same frequency even when separate
 d by non-contractile tissue. I will describe our efforts to understand how
  the embryonic heart start to beat using calcium imaging\, inhibitors of c
 hannel activity\, atomic force microscopy and comparative embryology.
LOCATION:Hodgkin Huxley Seminar Room\, Physiology Building\, Downing Site
END:VEVENT
END:VCALENDAR