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SUMMARY:Coordination of post-translational protein modification in human i
 nteraction networks - Dr. Ulrich Stelzl\,  Max Plank Institute for Molecul
 ar Genetics
DTSTART:20140616T130000Z
DTEND:20140616T140000Z
UID:TALK52998@talks.cam.ac.uk
CONTACT:Markus Ralser
DESCRIPTION:The cellular response to signals is frequently initiated by th
 e reversible covalent post-translational modification (PTM) of present \np
 roteins\, such as protein phosphorylation. A crucial point for understandi
 ng the information flow in cellular signaling is to define \nhow the vast 
 spectrum of PTMs are recognized by interacting molecules and how PTM-depen
 dent alterations are coordinated in protein interaction \nnetworks that le
 ad to signal propagation and dictate e.g. cellular cancer phenotypes.
LOCATION:Biochemistry Lecture Theatre\, Sanger Building\, Tennis Court Roa
 d
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