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SUMMARY:Genetic code expansion in vivo:  making proteins with novel proper
 ties - Dr Ambra Bianco\, MRC Laboratory of Molecular Biology\, University 
 of Cambridge
DTSTART:20141113T131000Z
DTEND:20141113T140000Z
UID:TALK54489@talks.cam.ac.uk
CONTACT:Felice Torrisi
DESCRIPTION:The genetic code is the system by which all the information ne
 eded for the growth\, living and reproducing of an organism is stored in t
 he DNA. The process of how the information is transferred from the DNA int
 o proteins has been the interest of a constantly growing number of scienti
 sts for the past few decades. In recent years a quite detailed understandi
 ng of the strategy all the living being use to extract this information fr
 om the genetic material and translate it into proteins\, and ultimately in
 to organisms\, has allowed to develop novel biotechnologies. One examples 
 of a new biotechnology is genetic code expansion\, by which a it is possib
 le to assign novel meaning to the genetic material and to introduce novel 
 synthetic molecules into proteins.\nGenetic code expansion has been used r
 ecently in order to incorporate novel non-canonical synthetic amino acid i
 nto proteins. It allows to give proteins novel properties that can greatly
  help our study of biologically relevant processes and at the same time op
 en many novel possibilities in the biomedical field.\nIn the past years we
  succeeded in incorporating non-canonical amino acids in a variety or orga
 nisms\, starting from the simple bacteria and moving on to higher level of
  complexity\, to yeast\, cultured mammalian cells and whole organisms\, su
 ch as the fruit fly Drosophila melanogaster. 
LOCATION:1 Newnham Terrace\, Darwin College
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