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SUMMARY:Watching and modelling limb development - Dr James Sharpe (Centre 
 for Genomic Regulation\, Barcelona)
DTSTART:20061117T093000Z
DTEND:20061117T100000Z
UID:TALK5538@talks.cam.ac.uk
CONTACT:Duncan Simpson
DESCRIPTION:While time-lapse imaging techniques have proven themselves to 
 be invaluable in understanding vertebrate organogenesis\, they have tended
  to focus on detailed qualitative observations of groups of cells within t
 he organ in question. By contrast\, despite its likely benefits to compute
 r modelling\, quantitative mapping of the global behaviour of an entire or
 gan has often been neglected. We have therefore been developing a new 4D i
 maging technique – time-lapse OPT – which aims to capture the physical
  dynamics and changing gene expression patterns of an entire growing mouse
  limb bud. This type of data will be used to improve our computer simulati
 ons of limb morphogenesis.
LOCATION:Kaetsu Centre\, New Hall
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