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SUMMARY:Genetic\, neuronal and experiential influences on olfactory percep
 tion in mice - Dr Darren Logan ( Wellcome Trust Sanger Institute)
DTSTART:20150113T160000Z
DTEND:20150113T170000Z
UID:TALK56220@talks.cam.ac.uk
CONTACT:Dr Hannah Rowland
DESCRIPTION:Mice\, like most mammals\, rely heavily on their sense of smel
 l for appropriate social interaction as well as identifying food and avoid
 ing predation. Olfactory perception relies on the detection of odours and 
 pheromones via many hundreds of different types of olfactory and vomeronas
 al receptors\, singularly expressed by olfactory sensory neurons (OSNs) in
  the nose. OSNs die and are replenished throughout life\, offering a mouse
  the opportunity to modify its olfactory capacity over time.\nI will prese
 nt our investigations into variance in olfactory perception in laboratory 
 mice at three levels: genetic\, neuronal and experiential\, using high-thr
 oughput genomic\, transcriptomic and olfactory receptor screening technolo
 gies. Our results suggest that the same environment smells differently to 
 each individual mouse\, and that multiple  mechanisms contribute to this v
 ariance in sensory perception. I will discuss the evolutionary and behavio
 ural implications of this finding.
LOCATION:Main Lecture Theatre\, Department of Zoology
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