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SUMMARY:&quot\;Fundamentals of a Novel Ionization Process and Implications
  for Materials Characterization using Mass Spectrometry&quot\; - Sarah Tri
 mpin\, Wayne State University
DTSTART:20141124T110000Z
DTEND:20141124T123000Z
UID:TALK56376@talks.cam.ac.uk
CONTACT:Dr Nino Nikolovski
DESCRIPTION:The introduction of electrospray ionization (ESI) and matrix-a
 ssisted laser desorption/ionization (MALDI) for the mass spectrometric ana
 lysis of peptides and proteins had a dramatic impact on biochemistry. Sara
 h developed a new ionization technique that allows a wide variety of compo
 unds\, including peptides\, proteins\, and protein complexes to be transpo
 rted directly from a solid-state small molecule matrix to gas-phase ions w
 hen placed into the vacuum of a mass spectrometer without the use of high 
 voltage\, a laser\, or added heat. This matrix and vacuum assisted soft io
 nization method is suitable for the direct surface analysis of biological 
 materials\, including tissue\, via mass spectrometry.\n
LOCATION:Department of Biochemistry\, Hopkins Building\, Seminar Room 2
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