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SUMMARY:The mechanism by which calcium affects the circadian clock  - Carm
 en Marti (Webb Lab)
DTSTART:20150326T130000Z
DTEND:20150326T133000Z
UID:TALK56596@talks.cam.ac.uk
CONTACT:Stephanie Swarbreck
DESCRIPTION:Circadian clock allows organisms to anticipate daily light and
  temperature cycles. In plants\, circadian rhythms control many biological
  processes like gene expression and the circadian oscillations of cytosoli
 c-free Ca2+ ([Ca2+]cyt). Since the first model of the oscillator was propo
 sed\, the plant clock has been expanded into a complex network of intercon
 nected feedback loops including the cytosolic molecule\, cyclic adenosine 
 diphosphate ribose which was proposed to be required to drive circadian [C
 a2+]cyt oscillations and modulate the nuclear transcriptional feedback loo
 p of the Arabidopsis circadian oscillator. These findings and the scarce i
 nformation about the function of circadian [Ca2+]cyt oscillations in both 
 plants and animals\, raised the question about whether [Ca2+]cyt regulates
  the clock. \n\nI will present the different approaches undertaken in the 
 lab to demonstrate that Ca2+cyt is a switch in the Arabidopsis circadian c
 lock that regulates circadian clock gene expression. I will also show that
  calcium-binding Calmodulin Like Protein 23 (CML23) and CML24 act as Ca2+-
 signalling components that regulate the circadian network through genetic 
 interaction with CCA1 HIKING EXPEDITION (CHE).\n
LOCATION:Department of Plant Sciences\, Large Lecture Theatre
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