BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Talks.cam//talks.cam.ac.uk//
X-WR-CALNAME:Talks.cam
BEGIN:VEVENT
SUMMARY:Modelling by Natural Moves - Peter Minary\, University of Oxford
DTSTART:20150211T141500Z
DTEND:20150211T151500Z
UID:TALK57068@talks.cam.ac.uk
CONTACT:Lucy Colwell
DESCRIPTION:The development of conformational sampling algorithms capable 
 of advancing the impact of structural simulation on molecular biology will
  require synergistic adaptation of many methods and concepts.  If accompli
 shed\, coarse-grained or atomistic simulations can predict equilibrium fea
 tures of biological activity or functionally relevant molecular motion and
  aid experimental modelling and design at the nanometer scale. \n\nHere\, 
 we present an algorithm that enables rapid exploration of the conformation
 al space of large macromolecular machines and supports modelling with cust
 omizable (hierarchical) degrees of freedom.  Its impact on molecular (stru
 ctural) biology research is demonstrated through applications for computat
 ional epigenetics\, RNA based nanotechnology and macromolecular refinement
 .  \n
LOCATION:Department of Chemistry\, Cambridge\, Pfizer lecture theatre
END:VEVENT
END:VCALENDAR