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SUMMARY:Growth and form of the gut - Dr Thiery Savin\, Department of Engin
 eering\, Cambridge University 
DTSTART:20150306T140000Z
DTEND:20150306T150000Z
UID:TALK57351@talks.cam.ac.uk
CONTACT:Dr Eileen Nugent
DESCRIPTION:The looping pattern in which intestines are folded within the 
 body cavity is conserved between individuals and is characteristic of spec
 ies. We use developmental and biophysical experiments (mathematical theory
  and both computational and physical models) to determine what drives the 
 looping\, focusing on the chick gut. We show that this reproducible struct
 ure is governed by simple mechanics\, related to the way the organ grows d
 uring embryogenesis. Throughout development\, the gut tube is anchored to 
 a muscular sheet called the mesentery which grows slower than the tube. Th
 e gut looping is then determined solely by the tissue-scale elasticity\, g
 eometry and relative rates of growth of the mesentery and the tube. This m
 odel accounts for variation in gut patterns\, during development and in a 
 range of species including quail\, finch and mouse.\n
LOCATION:Pippard Lecture Theatre\, Cavendish Laboratory
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