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SUMMARY:Ligand-mediated interactions between lipid vesicle: tuneable poros
 ity and negative thermal expansion in lipid-DNA phases. - Lorenzo Di Miche
 le
DTSTART:20150219T120000Z
DTEND:20150219T130000Z
UID:TALK57419@talks.cam.ac.uk
CONTACT:Salvatore Tesoro
DESCRIPTION:\nIn the last decade DNA has become routinely used to drive th
 e self-assembly of Brownian objects\, including colloids an nanoparticles.
 \nIn these systems\, the particles are coated with DNA tethers\, that bind
  to each other via selective and reversible Watson-Crick be pairing.\nRece
 ntly the same approach has been applied to more compliant units\, includin
 g emulsion droplets and lipid vesicles.\nIn these systems\, the deformabil
 ity of the substrates couples with the already complex statistical mechani
 cs of multivalent interactions.\nMoreover\, due to the liquid nature of th
 e interfaces\, DNA tethers can diffuse and rearrange\, giving rise to nont
 rivial entropic contributions to the free energy.\nWe recently investigate
 d the emergent thermal response of systems of networks of DNA-functionalis
 ed lipid vesicles\, leading to tuneable porosity and negative thermal expa
 nsion [Nature Communications 6:5948 2015].\nI will discuss experimental fi
 ndings and compare them with the predictions of a detailed analytical mode
 l.\nThe results highlight the importance of entropic contributions to the 
 coupling between the DNA tethers and the morphology of the substrates.
LOCATION:TCM Seminar room\, 530 Mott building
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