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SUMMARY:C Dots: Highly Fluorescent Silica Nanoparticles for Materials and 
 Life Sciences Applications - Prof Uli Wiesner\, Department of Materials Sc
 ience &amp\; Engineering\, Cornell University
DTSTART:20061110T141500Z
DTEND:20061110T151500Z
UID:TALK5752@talks.cam.ac.uk
CONTACT:Dr Kalin Dragnevski
DESCRIPTION:Fluorescent nanoparticles offer enormous scientific and techno
 logical promise as labels and photon sources for a range of biotechnologic
 al and information-technology applications such as biological imaging\, se
 nsor technology\, microarrays\, optical computing\, and display technology
 . Many applications require size-controlled\, monodisperse\, bright nanopa
 rticles that can be specifically conjugated to biological macromolecules o
 r arranged and positioned in higher-order structures and devices. As an al
 ternative to single molecule fluorophores and quantum dots\, silica-based 
 particles derived through the Stöber process hold particular promise sinc
 e they are non-toxic\, water soluble\, the silica chemistry is well establ
 ished and extremely versatile\, and silica is compatible with semiconducto
 r processing. Here we report on programs at Cornell’s Center for Materia
 ls Research (CCMR) and Nanobiotechnology Center (NBTC) to develop a novel 
 class of multifunctional silica-based fluorescent core-shell nanoparticles
  referred to as C-dots. Results on C-dot synthesis and characterization ar
 e discussed and first materials and life sciences applications are demonst
 rated. \n\nReferences\n1.) H. Ow\, D. R. Larson\, M. Srivastava\, B. A. Ba
 ird\, W. W. Webb\, U. Wiesner\, Bright and Stable Core-Shell Fluorescent S
 ilica Nanoparticles\, Nanoletters 5 (2005)\, 113-117.\n\n2.) A. Burns\, P.
  Sengupta\, T. Zedayko\, B. Baird\, U. Wiesner\, Core-Shell Fluorescent Si
 lica Nanoparticles for Chemical Sensing:  Moving towards Single Particle L
 aboratories\, Small 2 (2006) 723-726.\n\n3.) A. Burns\, H. Ow\, U. Wiesner
 \, Fluorescent Core-Shell Silica Nanoparticles: Towards “Lab on a Partic
 le” Architectures for Nanobiotechnology\, Chem. Soc. Rev. 35 (2006)\, 10
 28-1042.\n
LOCATION:IRC in Superconductivity Seminar Room\, Cavendish Laboratory
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