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SUMMARY:Probing the mechanics of growth of a bacterial microcolony - Marie
 -Cecilia Duvernoy\, ENS\, Paris
DTSTART:20150212T130000Z
DTEND:20150212T140000Z
UID:TALK57827@talks.cam.ac.uk
CONTACT:Hugo Wioland
DESCRIPTION:Timelapse microscopy is a largely used technique for studying 
 microbes\, and especially rod-shaped bacteria like the model organism E. c
 oli. However\, so far\, the mechanics of growth of these organisms in such
  conditions have not been investigated. \nMoreover\, in a physiological pr
 ospective\, interfaces are privileged areas where bacteria can settle sess
 ile colonies structured in biolms. Addressing the question of the morphog
 enesis in early stage of the colony development may give us some hints of 
 how bacteria manage to optimize a balance between the access to environmen
 tal resources and the cell-cell interactions. By performing laser ablation
  and traction force microscopy on growing micro-colonies\, we showed that 
 there is an asymmetric adhesion between the pre-existing and the newly for
 med poles of the bacteria. This drives the transition from a rod-shaped ba
 cteria with a strong linear symmetry to a two-dimensional the micro-colony
 . By measuring stresses developed by different micro-organisms\, we are st
 arting to get an insight of how these mechanical forces play a role in the
  whole colony shaping.\n
LOCATION:MR14\,  Centre for Mathematical Sciences\, Wilberforce Road\, Cam
 bridge
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