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SUMMARY:Who’s Afraid of Fractional Order Laplace? - Clara Ionescu\, Ghen
 t University
DTSTART:20150408T130000Z
DTEND:20150408T140000Z
UID:TALK57914@talks.cam.ac.uk
CONTACT:Tim Hughes
DESCRIPTION:We are now in the pioneering position where clinicians with th
 eir stethoscopes poised over the healthy heart\, radiologists tracking the
  blood flow\, and physiologists probing the nervous system\, are all explo
 ring the frontiers of chaos and fractals. Two concepts are necessary to be
  introduced: a) chaos theory says that a very minor disturbance in initial
  conditions leads to an entirely different outcome\; and b) fractals are s
 elf-similar structures on many or all scales (i.e. the principle of regula
 rity and order) [1\,2\,3]. These topics are central concepts in the new di
 scipline of nonlinear dynamics developed in physics and mathematics – se
 e Figure 1.\n\nHowever\, the most compelling applications of these abstrac
 t concepts are not in the physical sciences [4]\, but in medicine\, where 
 fractals and chaos may change radically long-held views about order and va
 riability in health and disease [5]. A transition to a more ordered or les
 s complicated state may be an indicative of disease (or equivalent a chang
 e in the nominal activity). Investigators have\, only in the past 5 years 
 or so\, discovered that the heart and other physiological systems may beha
 ve most erratically when they are young and healthy (i.e. random fractal p
 roperties\, power law dynamics\, can be well characterized by cascaded imp
 edance models). Counter-intuitively\, increasingly regular dynamic pattern
 s accompany aging and disease (i.e by using Fourier analysis tools one can
  detect these locked dynamics) [6\,7\,8].\n\nThe last decades have shown a
 n increased interest in the research community to employ parametric model 
 structures of fractional-order for analyzing nonlinear biological systems 
 [8]. The concept of fractional-order (FO) -- or non-integer order -- syste
 ms refers to those dynamical systems whose model structure contains arbitr
 ary order derivatives and/or integrals [9\,10\,11]. The dynamical systems 
 whose model can be approximated in a natural way using FO terms\, exhibit 
 specific features: viscoelasticity\, diffusion and fractal structure [12\,
 13\,14].\n \nHowever\, the theoretical concepts of fractals\, chaos and mu
 ltiscale analysis have not yet been enabled breakthrough mainly due to a l
 ack of awareness within the research community.\n\nFor further details of 
 the speaker and details of referenced work\, see http://www-control.eng.ca
 m.ac.uk/Main/ControlSeminarSlides or contact <a href="http://talks.cam.ac.
 uk/user/show/33890">Tim Hughes</a>.
LOCATION:Cambridge University Engineering Department\, LR3B
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