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SUMMARY:Activation and differentiation of human ILC3 - Chiara Romagnani\, 
 Berlin
DTSTART:20150515T120000Z
DTEND:20150515T130000Z
UID:TALK57996@talks.cam.ac.uk
CONTACT:Dr Tennie Videler
DESCRIPTION:Group 3 innate lymphoid cells (ILC3) are defined by the expres
 sion of RORγt\, which is selectively required for their development. ILC3
  produce IL-22 and other pro-inflammatory cytokines and contribute to the 
 defense against extracellular bacteria and Candida sp. Here we will discus
 s our findings on the characterization of human ILC3 and the signals drivi
 ng their activation and differentiation. Moreover\, we will discuss the re
 cent identification of the lineage-specified progenitor cells of human ROR
 γt+ ILC3 and their developmental site after birth remain. \n
LOCATION:MPLT\, MRC-LMB\, Francis Crick Avenue\, Cambridge Biomedical Camp
 us\, CB2 0QH
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