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SUMMARY:Finding Shared Causal Variants Between Diseases - Mary Fortune
DTSTART:20150308T140000Z
DTEND:20150308T143000Z
UID:TALK58318@talks.cam.ac.uk
CONTACT:George Fortune
DESCRIPTION:We know that there are many genetic loci associated with multi
 ple autoimmune diseases. However demonstrating that a variant is associate
 d with two traits is insufficient to establish causality for both\; the tr
 ue causal variants may be distinct but in linkage disequilibrium. I develo
 ped a statistical test to study whether two diseases share distinct or com
 mon variants in a given genetic region. By using this algorithm to leverag
 e information across datasets\, I was also able to identify novel disease 
 associations.
LOCATION:Winstanley Lecture Theatre
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