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SUMMARY:Analysis of complex phenotypes in genomics - Sylvia Richardson\, M
 RC Biostatistics Unit
DTSTART:20150522T133000Z
DTEND:20150522T143000Z
UID:TALK58614@talks.cam.ac.uk
CONTACT:20082
DESCRIPTION:In this talk\, I will discuss some of our recent work in the a
 rea of statistical genomics\, aimed at improving our biological understand
 ing of complex phenotypes.  Multiple layers of molecular phenomena are inv
 olved in the path between genes and disease. To better exploit the structu
 re of the rich biological data that is currently being collected\, statist
 ical models of the variations within and the interplay between different l
 ayers of genomics structures are constructed.  Generic Bayesian hierarchic
 al model building ideas and algorithms have been tailored for this purpose
 . In this talk I will discuss three areas: refining GWAS\, modelling expre
 ssion data\, and analysing ontology data and illustrate the modelling stra
 tegy on case studies.
LOCATION:MR12\,  Centre for Mathematical Sciences\, Wilberforce Road\, Cam
 bridge
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