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SUMMARY:Multiscale modelling of polymers at the soft-bio interface - Paola
  Carbone\, University of Manchester
DTSTART:20150506T131500Z
DTEND:20150506T141500Z
UID:TALK58737@talks.cam.ac.uk
CONTACT:Lucy Colwell
DESCRIPTION:The behaviour of polymers at a liquid/liquid interface has bec
 ome increasingly technologically important in recent years. For example\, 
 many of the self-assembly processes involving macromolecules occur at such
  interfaces  and one of the most common chemical processes used to produce
  polymer nanoparticles −the solvent displacement method− involves the 
 diffusion of the polymer chains from a good solvent\, where the polymer in
 itially dissolves\, to a non-solvent where the nanoparticles are formed.  
 Finally\, polymer-based drug nanocarriers (either nanoparticles or micelle
 s) are becoming increasingly popular in drug delivery and their behaviour 
 at fluid interfaces (such as a lipid/water boundary) should be properly un
 derstood in order to predict their biological activity. Here we show how u
 sing a multiscale approach it is possible to gain a detailed picture of th
 e thermodynamic stability of  homo- and co-polymers at fluid interfaces sp
 anning from universal rules valid to any polymer systems at high dilution 
 to the specific cases of amphiphilic linear and branched polymers.
LOCATION:Department of Chemistry\, Cambridge\, Pfizer lecture theatre
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