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SUMMARY:“The AML Genome(s): Mutations in Four Dimensions” - Dr. Timoth
 y J. Ley (Professor of Genetics\, Washington University School of Medicine
 \, St. Louis\, MO
DTSTART:20150604T153000Z
DTEND:20150604T163000Z
UID:TALK59540@talks.cam.ac.uk
CONTACT:Sylvie Robinson
DESCRIPTION:Dr. Timothy Ley received his BA from Drake University\, his MD
  degree from Washington University Medical School\, and performed his inte
 rnal medicine residency at Massachusetts General Hospital.  He completed f
 ellowships in Hematology and Oncology at the NIH and at Washington Univers
 ity\, and jointed the faculty at Washington University in St. Louis in 198
 6.  He now holds the Lewis T. and Rosalind B. Apple Chair in Oncology\, is
  Professor of Medicine and of Genetics at Washington University\, and serv
 es as Director of the Stem Cell Biology Section in the Department of Medic
 ine\, and Associate Director of The Genome Institute (for Cancer Genomics)
 .  Ley is a past president of the American Society for Clinical Investigat
 ion\, past treasurer of the American Association of Physicians\, a fellow 
 of AAAS and the American Academy of Arts and Sciences\, and a member of th
 e Institute of Medicine.  He was the 2012 recipient of the E. Donnall Thom
 as Prize from the American Society of Hematology.  He has developed approa
 ches to reactivate fetal hemoglobin synthesis for patients with hemoglobin
 opathies\, defined the role of the perforin/granzyme system for the functi
 on of cytotoxic and regulatory T cells\, and has performed pioneering stud
 ies that have defined the genomics of acute myeloid leukemia. He led the t
 eam at Washington University that sequenced the first human cancer genomes
 .  He has written extensively about the physician-scientist career path\, 
 and was a key advocate for establishing the extramural Loan Repayment Prog
 rams at the NIH.  He has mentored more than 50 pre- and post-doctoral fell
 ows in his laboratory\; most hold research positions in academic medicine 
 or pharmaceutical companies.
LOCATION:CRUK Cambridge Research Institute - LiKa Shing Centre - Robinson 
 Way - Cambridge - CB2 0RE
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