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SUMMARY:Epigenetic inheritance and parent-of-origin effects - Professor An
 ne Ferguson Smith\, Department of Genetics
DTSTART:20151123T180000Z
DTEND:20151123T190000Z
UID:TALK59590@talks.cam.ac.uk
CONTACT:Beverley Larner
DESCRIPTION:Abstract:  What is epigenetic inheritance and why is it import
 ant?  Epigenetics means ‘above’ or ‘on top of’ genetics. In biolog
 y and biomedical science today\, it is a term used to describe chemical mo
 difications to our DNA and to our chromosomes that mark our genetic materi
 al and affect both how our DNA is packaged into chromosomes and how our ge
 nes are regulated. In the different cells in our body\, these marks change
  during development and during disease\, but also they can be stably inher
 ited from one cellular generation to the next to maintain the specific chr
 omosome states. So\, can these marks also be transmitted from one generati
 on to the next and what might be the impact of this?   In this presentatio
 n\, I will discuss the relationship between the genome and the epigenome\,
  present some paradigms that have shed light on the function of epigenetic
  states and consider some of the unanswered questions that have an impact 
 on the role of epigenetics in health and disease. 
LOCATION:Bristol-Myers-Squibb Lecture theatre\, Department of Chemistry
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