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SUMMARY:Computational Neuroscience Journal Club - Dylan Festa (University 
 of Cambridge)
DTSTART:20150526T150000Z
DTEND:20150526T160000Z
UID:TALK59604@talks.cam.ac.uk
CONTACT:Guillaume Hennequin
DESCRIPTION:Dylan Festa will cover:\n* Diverse synaptic plasticity mechani
 sms orchestrated to form and retrieve memories in spiking neural networks\
 n* F Zenke\, E J Agnes and W Gerstner\n* Nature Communications\, 2015\n* h
 ttp://www.nature.com/ncomms/2015/150421/ncomms7922/full/ncomms7922.html\n\
 nSynaptic plasticity\, the putative basis of learning and memory formation
 \, manifests in various forms and across different timescales. Here we sho
 w that the interaction of Hebbian homosynaptic plasticity with rapid non-H
 ebbian heterosynaptic plasticity is\, when complemented with slower homeos
 tatic changes and consolidation\, sufficient for assembly formation and me
 mory recall in a spiking recurrent network model of excitatory and inhibit
 ory neurons. In the model\, assemblies were formed during repeated sensory
  stimulation and characterized by strong recurrent excitatory connections.
  Even days after formation\, and despite ongoing network activity and syna
 ptic plasticity\, memories could be recalled through selective delay activ
 ity following the brief stimulation of a subset of assembly neurons. Block
 ing any component of plasticity prevented stable functioning as a memory n
 etwork. Our modelling results suggest that the diversity of plasticity phe
 nomena in the brain is orchestrated towards achieving common functional go
 als.
LOCATION:Cambridge University Engineering Department\, CBL\, BE-438 (http:
 //learning.eng.cam.ac.uk/Public/Directions)
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