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SUMMARY:Testing a Perceptual Theory of Amnesia with fMRI:  Perceptual Inte
 rference Disrupts Neural Signatures of Familiarity in Visual Cortex - Dr R
 osie Cowell - Computational Memory &amp\; Perception Lab\, Psychology\, Un
 iv. of Massachusetts Amherst
DTSTART:20150622T120000Z
DTEND:20150622T130000Z
UID:TALK59935@talks.cam.ac.uk
CONTACT:Lorraine Coulson
DESCRIPTION:One theory of amnesia assumes that (1) in the absence of media
 l temporal lobe (MTL) structures\, familiarity judgements are based upon r
 epresentations of simple visual features in posterior visual cortex\, and 
 (2) these representations are susceptible to perceptual interference. Usin
 g an incidental 1-back repetition detection task during fMRI\, we presente
 d a series of object photographs to assess whether perceptual interference
  disrupted neural signatures of novelty. Novelty was indexed by repetition
  reduction (RR) of the BOLD signal. In posterior visual cortex\, we expect
 ed to see less RR at the end of the series – after perceptual interferen
 ce – than at the beginning\; this would indicate that perceptual interfe
 rence disrupts the neural signature of novelty in these brain regions. In 
 the ‘high interference’ condition\, interfering objects presented in t
 he middle of the series were perceptually similar to those at the beginnin
 g and end (for which RR was measured). In the ‘low interference’ condi
 tion\, interfering objects were dissimilar. Consistent with the theory\, R
 R was reduced by interference in a posterior visual region\, during high i
 nterference relative to low interference series of objects. 
LOCATION:Kenneth Craik Room\, Craik Marshall Building\, Downing Site\, Cam
 bridge
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