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SUMMARY:Light Sleep - Gero Miesenboek University of Innsbruck
DTSTART:20151102T163000Z
DTEND:20151102T180000Z
UID:TALK60193@talks.cam.ac.uk
CONTACT:P.H. Marchington
DESCRIPTION:Ozcan\, G. G. & Rihel J A Drosophila Circuit Feels the (Sleep)
  Pressure. 2014. Neuron 81\, 720 – 722. \n\nMiesenboek\, G. 2009.  The O
 ptogenetic Catechism. Science\, Vol 326\, 395 – 399. An emerging set of 
 methods enables an experimental dialogue with biological systems composed 
 of many interacting cell types—in particular\, with neural circuits in t
 he brain. These methods are sometimes called “optogenetic” because the
 y use light-responsive proteins (“opto-”) encoded in DNA (“-genetic
 ”). Optogenetic devices can be introduced into tissues or whole organism
 s by genetic manipulation and be expressed in anatomically or functionally
  defined groups of cells. Two kinds of devices perform complementary funct
 ions: Light-driven actuators control electrochemical signals\, while light
 -emitting sensors report them. Actuators pose questions by delivering targ
 eted perturbations\; sensors (and other measurements) signal answers. Thes
 e catechisms are beginning to yield previously unattainable insight into t
 he organization of neural circuits\, the regulation of their collective dy
 namics\, and the causal relationships between cellular activity patterns a
 nd behaviour.\n
LOCATION:The Hodgkin Huxley Seminar Room\, Department of Physiology Develo
 pment and Neuroscience
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