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SUMMARY:The Order Nidovirales: a serendipitous finding - Professor Marian 
 C. Horzinek\, Department of Infectious Diseases and Immunology\, Faculty o
 f Veterinary Medicine\, Utrecht University\, The Netherlands
DTSTART:20070214T163000Z
DTEND:20070214T173000Z
UID:TALK6124@talks.cam.ac.uk
CONTACT:4872
DESCRIPTION:Professor Horzinek studied veterinary medicine in Germany at G
 iessen and Hannover Universities\, from 1956 to 1961. A year later he obta
 ined his Doctor of Veterinary Medicine (Dr. med.vet.) and in 1970 he gaine
 d his 'Habilitation' (a PhD equivalent) in virology. He began his career i
 n virology at the Public Health Laboratory in Hannover\, where he worked a
 s a research fellow of the Deutsche Forschungsgemeinschaft. He later helpe
 d to establish the Chair of Virology at Hannover Veterinary School\, and t
 hen spent a year as a research fellow at the Instituto Venezolano de Inves
 tigaciones Cientificas in Caracas\, Venezuela. \n\n \n\nUpon his return\, 
 he became Head of the Exotic Diseases Division at the Federal Research Ins
 titute for Animal Virus Diseases in Tübingen\, Germany. In 1971\, he move
 d to The Netherlands where he was appointed Head of Department and Profess
 or of Virology and Virus Diseases at the Faculty of Veterinary Medicine\, 
 Utrecht University. Since 1992\, Professor Horzinek has been director of U
 trecht University's Institute of Veterinary Research\, and in 1996 Profess
 or Horzinek established\, and has since directed\, the Graduate School Ani
 mal Health.\n\n \n\nProfessor Horzinek has been honored with several title
 s outside the Veterinary Faculty of Utrecht\, namely: Associate Professor 
 at the Veterinary School in Hannover\, Germany\, Courtesy Professor at the
  College of Veterinary Medicine\, Cornell University\, USA\, and Clinical 
 Professor of Virology at the School of Veterinary Medicine\, University of
  California\, Davis\, USA.\n\n \n\nDuring his career so far\, Professor Ho
 rzinek has gained a number of prizes and awards from research organisation
 s in Giessen (Germany)\, Liège (Belgium)\, Geelong (Australia)\, Yokohama
  (Japan) and Amsterdam (The Netherlands)\, and honorary doctorates from th
 e University of Ghent (Belgium) and the Veterinary School in Hannover (Ger
 many).\n\n \n\nHis publications include in excess of 250 scientific papers
  and more than 30 books and monographs\, a handbook and many CD-ROM articl
 es. He has been an editor or an editorial board member for scientific jour
 nals published in the Netherlands\, Belgium\, Great Britain\, Germany\, Au
 stria\, France and Italy. At present\, Professor Horzinek is Editor-in-Chi
 ef for the Elsevier published journal ‘Veterinary Microbiology'. He is t
 he founding president of the European Society of Feline Medicine\, a scien
 tific society based in the UK\, and is a founding member of the German Ges
 ellschaft für Kynologische Forschung\, a fund-raising initiative for vete
 rinary research.\n\n \n\nHis most recent\, and arguably most ambitious\, p
 roject to date is the establishment of the online veterinary research jour
 nal\, Veterinary Sciences Tomorrow. This new venture will be a full-time o
 ccupation as soon as he relinquishes his other responsibilities at the Utr
 echt Faculty of Veterinary Medicine in Utrecht.\n\n \n\nMajor research acc
 omplishments\n\nTubingen:\n\n. first description of the structure and morp
 hology of classical swine fever virus\n\n. first evidence for the existenc
 e of an icosahedral capsid symmetry in enveloped RNA viruses\n\n(alphaviru
 ses]\;\n\n. elucidation of capsid structure in pesti-\, arteri- and rubivi
 ruses\n\n. definition and naming of the pestiviruses\n\n. first descriptio
 n of immunizing\, non-infectious immune-stimulating virion subunits\n\n(la
 ter rediscovered and termed ISCOMS]\n\nUtrecht:\n\n. first purification an
 d ultrastructural analysis of lactic dehydrogenase virus\n\n. characteriza
 tion and definition of arteriviruses\n\n. etiology\, molecular definition\
 , immunopathogenesis and diagnosis of feline peritonitis.\n\nfirst descrip
 tion of a papillomavirus in birds and characterization\n\n. independent in
 itiation of subgenomic coronavirus mRNAs synthesis\n\n. antigenic relation
 ships between porcine\, feline and canine coronaviruses\n\n. definition of
  the 'corona-like superfamily' of viruses\n\n. definition\, naming and int
 roduction of toroviruses as a new taxonomic cluster into virology\n\n. hep
 tade repeat in corona- and torovirus spike protein\n\n. genetic and antige
 nic drift in coronaviruses\n\n. virus evolution: RNA-recombination between
  coronaviruses\, toroviruses and a hemagglutinin-esterase gen\;\n\npolymer
 ase relationships\n\n. immunomodulation and pathogenicity of cytokines in 
 viral infections\n\n. antigenic relatedness of feline immunodeficiency vir
 us and equine infectious anemia virus.\n\nsuccessful chemotherapy of felin
 e immunodeficiency virus infection (feline AIDS]\n\n. coronavirus assembly
 \; first in vitro construction of coronavirus-like particles\n\n. establis
 hment of the Nidovirales\, the second order in animal virus taxonomy\n\n \
 n
LOCATION:Lecture Theatre 1\, Department of Veterinary Medicine
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