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SUMMARY:MODIFYING THE GLIAL SCAR TO PROMOTE REPAIR AND REGENERATION AFTER 
 SPINAL CORD INJURY - Professor Joel Levine\, Multiple Sclerosis Collaborat
 ive Research Center\, USA
DTSTART:20151125T120000Z
DTEND:20151125T130000Z
UID:TALK61615@talks.cam.ac.uk
CONTACT:Shannon Tinley-Browne
DESCRIPTION:The glial scar that forms after spinal cord injury is a comple
 x assembly of diverse cellular elements and extracellular matrix molecules
  that is considered a physical and biochemical barrier to successful axon 
 regeneration. I will discuss several different molecular and cellular appr
 oaches to modifying the formation and properties of the glial scar and the
  effects of these manipulations on axonal regrowth and functional recovery
  after experimental injury to the thoracic spinal cord. These results demo
 nstrate that the glial scar is not an insurmountable barrier to recovery. 
 The approaches we have developed may have therapeutic potential.  
LOCATION:Brain Repair Centre\, Forvie Site\, Robinson Way
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