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SUMMARY:Endodermal contribution to orofacial structures in non-teleost fis
 hes: How ancient is the pre-oral gut? - Martin Minařík (Charles Universi
 ty\, Prague)
DTSTART:20151118T130000Z
DTEND:20151118T140000Z
UID:TALK61644@talks.cam.ac.uk
CONTACT:Marcia Kishida
DESCRIPTION:Despite the wide variety of adaptive modifications in oral and
  branchial region of vertebrates\, their early oropharyngeal development i
 s considered rather uniform. From anterior to posterior\, it comprises seq
 uential formation of mouth and pharyngeal pouches\, but the precise germ l
 ayer interactions have been studied on a limited number of model organisms
  so far. We have collected and analysed a complete series of embryonic sta
 ges of African bichir\, American gar\, and European sturgeon\, representat
 ives of three most basal (non-teleost) fish lineages. In all these species
  the standard vertebrate setting of foregut development is preceded by a u
 nique process of anterior foregut expansion which gives rise to a distinct
  “pre-oral gut”. This pre-oral gut epithelia eventually extend to the 
 external head surface where they contribute to various facial structures\,
  including lips\, sensory barbels and cement glands. This represents a fir
 st example of endodermal contribution to external head structures in verte
 brates. Based on our analysis we conclude that this mode of foregut format
 ion might be ancestral to all ray-finned fishes and has been lost only sec
 ondarily in teleosts due to the radical changes in their early embryonic d
 evelopment. Moreover\, similar developmental processes described in tunica
 tes and cephalochordates suggest that the evolutionary origin of the pre-o
 ral gut might be nested even deeper in chordate history.
LOCATION:Part II Lecture Theatre\, Department of Zoology
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