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SUMMARY:IMMUNOLOGICAL SELF - Philippa Marrack\, Howard Hughes Medical Inst
 itute\, Denver\, Colorado
DTSTART:20070302T173000Z
DTEND:20070302T183000Z
UID:TALK6195@talks.cam.ac.uk
CONTACT:Janet Gibson
DESCRIPTION:The immune response protects individuals against infections. I
 n order to do this effectively the immune system must be able to distingui
 sh between invading organisms and its own host\, attacking the former whil
 st leaving the latter unharmed. This is not such an easy matter given that
  invading organisms occur in many forms\, as viruses\, bacteria\, yeasts\,
  worms and so on and that the invaders are constantly mutating to avoid at
 tack by their potential hosts. Given the difficulty of the task it is not 
 surprising that the immune system has evolved many ways to distinguish bet
 ween invaders and its own host. The mechanisms used fall into two classes.
  One class involves recognition of features of the invader which are not p
 resent on the host. If this type of recognition occurs\, the target is des
 troyed. Another class involves recognition of features of the host which a
 re not present on the invader. If this type of recognition occurs\, the im
 mune response is inhibited and the target is not destroyed. Thus the immun
 ologic self is defined in two ways\, either by the absence of something fo
 reign and/or by the presence of something familiar. 
LOCATION:LMH\, Lady Mitchell Hall
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