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SUMMARY:Systems approaches towards understanding temperature signalling in
  plants - Dr Philip Wigge\, Sainsbury Laboratory.
DTSTART:20151111T140000Z
DTEND:20151111T150000Z
UID:TALK61951@talks.cam.ac.uk
CONTACT:38916
DESCRIPTION:Plants are sessile\, and must therefore adapt their growth and
  development to their environment. A major environmental variable is ambie
 nt temperature. Annual variations in temperature provide plants with impor
 tant seasonal information\, and 24 h temperature cycles are important for 
 entraining the circadian clock. Temperature extremes are also a major thre
 at to crop yield\, with yields decreasing about 10 % for every 1 ºC incre
 ase in mean temperature.\n\nDespite the importance and interest of tempera
 ture signalling in plants\, very little is known about the underlying mech
 anisms by which temperature is sensed and how this information is integrat
 ed into development. To address this question\, our laboratory has adopted
  a variety of forward and reverse genetic approaches to identify key nodes
  in the temperature perception pathways. These have revealed an important 
 connection between chromatin status and temperature signalling. Because te
 mperature has global scale effects on a large proportion of the transcript
 ome\, this problem is ideally suited to being addressed with systems biolo
 gy approaches. Recent advances in high throughput sequencing now provide t
 ools to dynamically assay the behavior of transcription factors\, chromati
 n\, resulting transcripts as well as translational efficiency genome-wide.
  I will outline some of our progress in this area as well as topics that a
 re currently under study and would make good MPhil projects.\n\nReading:\n
 Wigge PA (2013)\nCurr Opin Plant Biol. 16:661-6\nAmbient temperature signa
 lling in plants.\n\n
LOCATION:MR4\, Centre for Mathematical Sciences\, Wilberforce Road\, Cambr
 idge
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